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Registros recuperados: 23 | |
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Camplesi,A.C.; Rivera,G.G.; Bonacin,Y.S.; Paula,V.B.; Lacerda Neto,J.C.; Moya-Araujo,C.F.. |
RESUMO O presente trabalho tem por objetivo relatar um caso de envenenamento botrópico em um equino, fêmea, seis anos de idade, da raça Quarto de Milha, pesando 460kg, que foi atendido no hospital veterinário da FCAV/Unesp, Campus de Jaboticabal, SP. No exame clínico, observou-se aumento bilateral de narina, com extrema sensibilidade ao toque, presença das marcas da presa da serpente na região rostral de focinho, mucosas róseas com petéquias. No exame de sangue, pôde-se detectar alteração no tempo de coagulação sanguínea (>30 minutos). O animal permaneceu internado, sendo instituída a seguinte terapia: soro antiofídico polivalente, transfusão de plasma sanguíneo equino, fluidoterapia intensa, flunixin meglumine e sulfa associado ao trimetoprim. A... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops; Acidente ofídico; Terapêutica. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000400815 |
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Sobrinho, A. P.; Meirelles, L. G.; Dacasa, J. A. L.; Cunha, L. E. R.; Takeuti, V. Y.; Parreiras, L. P.; Mpalantinos, M. A.; Castanheira, P. N.. |
O processo de produção de plasma hiperimune no Instituto Vital Brazil seguiu um calendário próprio, tendo como objetivo o monitoramento dos eqüinos para a avaliação do da saúde dos animais. O estudo foi baseado na realização de hemogramas periódicos, em vinte nove cavalos imunizados e seis cavalos não imunizados. Foram colhidas amostras antes da inoculação, das sangrias de produção e após as reinfunsões das hemácias, totalizando em 350 amostras. Variações pouco significativas foram observadas nas análises de leucograma e eritrograma no grupo experimental quando comparados ao grupo controle. Após o período de repouso foi observada uma recuperação dos valores hematológicos (96,4% dos hematócritos e 98,7% dos eritrócitos), o que facilitou o rápido retorno... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemograma; Bothrops; Plasmaferese; Cavalos. |
Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/5404 |
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Fonteque, Joandes Henrique; de Barros Filho, Ivan Roque; Sakate, Michiko. |
The objective of this review is to present information about Bothrops envenomation in domestic animals, describing the major Bothrops species, animals sensitivity to venom, pathogenicity, clinical signs, sequelae and complications, laboratory and necropsy findings, diagnosis, treatment and reactions to serum therapy. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops; Venomous animals; Bothrops accidents; Domestic animals bothrops; Animais peçonhentos; Acidente botrópico; Animais domésticos. |
Ano: 2001 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3311 |
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Setubal,SS; Pontes,AS; Furtado,JL; Kayano,AM; Stábeli,RG; Zuliani,JP. |
Envenomations caused by different species of Bothrops snakes result in severe local tissue damage, hemorrhage, pain, myonecrosis, and inflammation with a significant leukocyte accumulation at the bite site. However, the activation state of leukocytes is still unclear. According to clinical cases and experimental work, the local effects observed in envenenomation by Bothrops alternatus are mainly the appearance of edema, hemorrhage, and necrosis. In this study we investigated the ability of Bothrops alternatus crude venom to induce macrophage activation. At 6 to 100 ¼g/mL, BaV is not toxic to thioglycollate-elicited macrophages; at 3 and 6 ¼g/mL, it did not interfere in macrophage adhesion or detachment. Moreover, at concentrations of 1.5, 3, and 6 ¼g/mL... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snake venom; Bothrops; Macrophages; Phagocytosis; Superoxide; Protein kinase C; Inflammation. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000400010 |
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Gallardo-Casas,CA; Guevara-Balcázar,G; Morales-Ramos,E; Tadeo-Jiménez,Y; Gutiérrez-Flores,O; Jiménez-Sánchez,N; Valadez-Omaña,MT; Valenzuela-Vargas,MT; Castillo-Hernández,MC. |
In Mexico, medicinal plants are widely used. The use of Randia aculeata by healers against snakebites has never been scientifically tested in relation to possible effects on blood parameters and muscle tissue damage. Interviews were carried out in Jamapa, Veracuz, Mexico, with local residents to collect information about the traditional use of Randia aculeata. In this locality, seven pieces of fruit from the plant are mixed in a liter of alcohol, and then administered orally against snakebites. By using histological techniques and a murine model, we explored its cytoprotective properties against the effects of Crotalus simus and Bothrops asper venoms. Possible protections provided by the plant against tissue damage to skeletal and cardiac muscles and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rubiaceae; Antivenoms; Bothrops; Crotalus; Cytoprotection. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300006 |
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Silva,NS; Silveira,JAS; Albernaz,TT; Campos,KF; Oliveira,CMC; Freitas,NFQR; Bomjardim,HA; Barbosa,JD. |
The present study reports a snakebite in a horse in the state of Pará, Brazil. At initial evaluation the animal was reluctant to walk and had tachycardia, tachypnea, severe lameness, bleeding on the pastern and swelling around the left hind leg. Blood samples from the bleeding sites, took on the first day, showed leukocytosis and neutrophilia, whereas biochemical values of urea and creatinine were significantly increased. The chosen treatment was snake antivenom, fluid therapy, antibiotics, anti-inflammatory agents and diuretic drugs. On the fourth day of therapy, the hematological values were within normal parameters. There was improvement related to the clinical lameness and swelling of the limb. However, a decrease in water intake and oliguria were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snakebites; Horses; Bothrops. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000400018 |
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Grazziotin,Felipe; Echeverrigaray,Sergio. |
The genetic relationships among 11 species of Bothrops found in Brazil were determined using random amplified fragment (RAPD) information. A total of 239 amplified bands were scored using 20 aleatory primers. Most of the bands (88.7%) were polymorphic. Phylogenetic analysis of the data determined three similarity groups within Bothrops: Group I- B. alternatus, B. neuwiedi, B. cotiara, and B. jararacusu; Group II- B. insularis, B. jararaca, and B. erythromelas; and Group III- B. moojeni, B. leucurus, and B. atrox. These groups coincided with those obtained by other methods, indicating that RAPD's could be a useful tool for the evaluation of genetic relationships at the interspecific level. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops; RAPD; Molecular markers; Genetic relationship. |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000300005 |
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TROIANO,J.C.; VIDAL,J.C.; GOULD,E.F.; HEKER,J.; GOULD,J.; VOGT,A. U.; SIMONCINI,C.; AMANTINI,E.; DE ROODT,A.. |
Blood samples of 50 healthy specimens from each of the following species: Bothrops alternatus, Bothrops jararacussu, Bothrops moojeni, and Bothrops neuwiedi diporus all kept in captivity were taken to determine the hematocrit (PCV) value, red blood cell count (RBC), total leukocyte (WBC) and differential leukocyte count, thrombocyte count, mean corpuscular volume (MCV), hemoglobin concentration (HbC), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). These hematological parameters were compared to those obtained from other Bothrops species. PCV values, RBC, hemoglobin, WBC count, and differential leukocyte count are within the range of values reported for other Bothrops species, while the thrombocyte count was... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hematology; Snakes; Bothrops; Captivity. |
Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200005 |
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Rodríguez,JP; De Marzi,MC; Maruñak,S; Teibler,P; Acosta,O; Malchiodi,EL; Leiva,LC. |
We examined the ability of IgG anti-crotalic PLA2 to cross-react with Bothrops spp. venoms, from snakes found in the northeast of Argentina. Immunoblotting and ELISA tests showed that IgG anti-crotalic PLA2 recognize antigens of bothropic venoms. Indirect hemolytic activity tests showed that the quantity of antibodies that neutralized 50% of Crotalus durissus terrificus venom (ED50: 2.1 mg IgG anti-crotalic PLA2/100 µg of venom) were also able to neutralize venom from other snakes in the following proportion: 34% of B. alternatus, 18% of B. diporus and 12% of B. jararacussu. Likewise, direct PLA2 activity neutralization tests showed a similar cross-neutralization pattern including 56% of B. alternatus, 29% of B. diporus and 30% of B. jararacussu. In... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops; Crotalus; PLA2; Neutralization; Cross-reaction. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300008 |
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Ferreira Junior,R. S.; Nascimento,N.; Martinez,J. C.; Alves,J. B.; Meira,D. A.; Barraviera,B.. |
ELISA was used to evaluate, accompany, and compare the humoral immune response of Swiss mice during hyperimmunization with native and Cobalt-60-irradiated (60Co) venoms of Bothrops jararaca, Bothrops jararacussu and Bothrops moojeni. Potency and neutralization were evaluated by in vitro challenges. After hyperimmunization, immunity was observed by in vivo challenge, and the side effects were assessed. The animals immunization with one LD50 of each venom occurred on days 1, 15, 21, 30, and 45, when blood samples were collected; challenges happened on the 60th day. Results showed that ELISA was efficient in evaluating, accompanying and comparing mouse immune response during hyperimmunization. Serum titers produced with natural venom were similar to those... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Venom; Irradiation; Bothrops; ELISA; Serum production; Detoxification. |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000400006 |
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JORGE,M. T.; RIBEIRO,L. A.. |
Envenomation caused by snakes of the Bothrops genus produces a lesion in the bite site and can result in extensive necrosis. The dead tissue can be secondarily infected by bacteria that come from the snake, and the bacteria can be inoculated at the moment of the bite. The bacteria that most commonly cause infection are the enterobacteria, mainly Morganella morganii, Proteus rettgeri, Enterobacter sp., and Escherichia coli. Group D streptococci including here Enterococcus sp. and the Bacteroides sp. are also involved. Based on a study of the sensibility of these bacteria, it has been suggested that this infection must be treated with chloramphenicol, as a sole antimicrobial agent, or with the combinations of benzylpenicillin or ampicillin with... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snakebite; Bothrops; Infection; Antimicrobial agents; Treatment. |
Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200002 |
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Costa,Tássia R.; Carone,Sante E. I.; Tucci,Luiz F. F.; Menaldo,Danilo L.; Rosa-Garzon,Nathalia G.; Cabral,Hamilton; Sampaio,Suely V.. |
Abstract Background: L-amino acid oxidases isolated from snake venoms (SV-LAAOs) are enzymes that have great therapeutic potential and are currently being investigated as tools for developing new strategies to treat various diseases, including cancer and bacterial infections. The main objective of this study was to make a brief evaluation of the enzymatic stability of two Bothrops LAAOs, one isolated from Bothrops jararacussu (BjussuLAAO-II) and the other from Bothrops moojeni (BmooLAAO-I) venoms. Methods and results: The enzymatic activity and stability of both LAAOs were evaluated by microplate colorimetric assays, for which BjussuLAAO-II and BmooLAAO-I were incubated with different L-amino acid substrates, in the presence of different ions, and at... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snake venom; Bothrops; L-amino acid oxidase; Enzymatic stability. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100327 |
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Balestrin,Rafael Lucchesi; Leitão-de-Araujo,Moema; Alves,Maria Lúcia Machado. |
In May 1987, a female of Bothrops jararaca (Wied, 1824), from Carazinho, Rio Grande do Sul (RS), Brazil, was placed in the same vivarium with a male of Bothrops neuwiedi Wagler, 1824 coming from Guaíba, RS. There, they stayed for aproximately ten months. In March 1988, it was observed a delivery of five live and two still born, among them six presented morphologic characteristics of B. neuwiedi and one of B. jararaca. After the female died, in April 1988, through necropsy, two fetusus were found, one near the cloaca and, both identified as B. neuwiedi. The morphologic analysis and the origin of the progenitors suggest the hypothesis that the litter was resulted of cross-breeding. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops; Hibridism; Captivity; Rio Grande do Sul; Brazil. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0073-47212002000100007 |
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Stuginski,DR; Fernandes,W; Tattersall,GJ; Abe,AS. |
Snakes that can ingest prey that are proportionally large have high metabolic rates during digestion. This great increase in metabolic rate (specific dynamic action - SDA) may create a significant augment in the animal's body temperature. The present study investigated postprandial thermogenesis in Bothrops moojeni. Briefly, two groups of snakes were fed meals equivalent to 17 ± 3% and 32 ± 5% of their body weight and were observed for 72 hours, in which thermal images of each snake were taken with an infrared camera in a thermostable environment with a constant air temperature of 30°C. The results showed a significant increase in snake surface temperature, with a thermal peak between 33 and 36 hours after feeding. The meal size had a great impact on the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops; Thermogenesis; Feeding behavior; Digestion. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000300008 |
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GUIDOLIN,R.; STEPHANO,M. A.; MORAIS,J. F.; SAKAGUTI,E. H.; PRADO,S. M. A.; FRATELLI,F.; VANCETTO,M. D. C.; HIGASHI,H. G.. |
The present investigation reveals the possibility of simultaneous immunization of horses with Bothrops or Crotalus snake venoms and Tetanus antigens for the production of anti-Bothrops-Tetanus or anti-Crotalus-Tetanus mixed serum, with high titers of the respective specific antibodies. Bothrops antivenoms with an average neutralizing titer of 4.16 mg venom/ml were obtained from plasma of horses with titers lower than 0.5 mg venom/ml when Tetanus antigens were not used. This suggests the existence of a synergism between Bothrops venoms and Tetanus antigens in the stimulation of the antibody response. The pooled plasma of the animals had a neutralizing titer of 21.0 mg/ml reference Bothrops venoms and 3,300 IU/ml to Tetanus antigens after purification by... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antivenoms; Immunization; Bothrops; Tetanus. |
Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301998000100007 |
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ROCHA,MARCELO C.; HARTMANN,PAULO A.; WINCK,GISELE R.; CECHIN,SONIA Z.. |
Viperid snakes are widely distributed in the South America and the greater distribution range of the family is found at the Crotalinae subfamily. Despite the abundance of this snakes along their geographic distribution, some ecological aspects remain unknown, principally at subtropical areas. In the present study, we evaluated the activity (daily and seasonal) and the use of the habitat by Bothrops diporus, B. jararaca andB. jararacussu, in an Atlantic Forest area at southern Brazil. We observed higher incidence of viperid snakes during the months with higher temperatures, while no snakes were found during the months with lower temperatures. The data suggest the minimum temperature as environmental variable with the greatest influence on the seasonal... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Parque Estadual do Turvo; Rio Grande do Sul; Atlantic Forest; Bothrops; Activity pattern. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000200695 |
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Tinoco,H. B.; Norberg,A. N.; Pile,E.; Carvalho,C. R. P.; Silva,D. A.; Guerra-Sanches,F.. |
The frequency of envenoming in Northwest counties of the Rio de Janeiro State, Brazil, from 1995 to 2000 was evaluated. Reports from the Municipal Secretariat of Health of these counties were used. The results demonstrated that, from 1997 to 1999, there was a shortage of notification, and 40 cases of envenomations caused by Bothrops snakes were registered. These cases were more common from February to October, and the lower limbs of male peasants were the mainly affected areas. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Poisonous snakes; Bothrops; Envenomations; Rio de Janeiro; Brazil. |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000100005 |
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Registros recuperados: 23 | |
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